莫西沙星联合头孢菌素类抗菌药物治疗社区获得性肺炎的疗效评价

2022-06-29李征洋

婚育与健康 2022年11期

李征洋

【摘要】目的：讨论社区获得性肺炎以莫西沙星+头孢菌素类抗菌药物治疗的效果。方法：选取2020年9月—2021年9月我院社区获得性肺炎患者106例，随机划成：对照、观察两组（各53例）。对照组莫西沙星治疗，观察组在对照组基础上增加头孢匹胺，比较两组的治疗总有效率、康复时间、细菌清除率。结果：观察组的治疗总有效率高于对照组（P<0.05）；观察组各症状康复时间短于对照组（P<0.05）；观察组细菌清除率高于对照组（P<0.05）。结论：莫西沙星+头孢匹胺的疗效可观，对社区获得性肺炎的效果好，细菌清除率高，利于各项症状的快速消失，值得肯定。

【关键词】莫西沙星；头孢菌素类抗菌药物；社区获得性肺炎；细菌清除率

Efficacy Evaluation of Moxifloxacin Combined with Cephalosporin Antibiotics in the Treatment of Patients with Community-Acquired Pneumonia

LI Zhengyang

Horqin Right Front Banner Peoples Hospital， Hinggan League， Hinggan League， Inner Mongolia 137400， China

【Abstract】Objective：To discuss the effect of moxifloxacin+cephalosporin antibiotics in the treatment of community-acquired pneumonia. Methods：From September 2020 to September 2021，106 patients with community-acquired pneumonia in our hospital were randomly divided into two groups：control group and observationgroup（53cases in each group）.The control group was treated with moxifloxacin，and the observation group was increased with cefpiramide on the basis of the control group.The treatment total efficiency，recovery time，and bacterial clearance rate of the two groups were compared.Results：The total effective rate of treatment in the observation group was higher than that in the control group（P<0.05）；The recovery time of each symptomin the observation group was shorter than that in the control group（P<0.05）；The bacterial clearance rate in the observation group was higher than that in the control group （P<0.05）.Conclusion：Moxifloxacin+cefpiramide has considerable curative effect，good effect on community-acquired pneumonia，high bacterial clearance rate，and is conducive to the rapid disappearance of various symptoms，which is worthy of recognition.

【Key Words】Moxifloxacin； Cephalosporin antibiotics； Community-acquired pneumonia； Bacterial clearance rate

社區获得性肺炎（Community Acquired Pneumonia，CAP）为医院外感染的一种肺部炎症，因感染病毒、细菌、衣原体、支原体等微生物所致[1]。患病后，患者会出现明显的咳嗽、咳痰、胸疼等症状，与上呼吸道感染的症状有着一定相似之处，但该疾病的死亡率更高，对患者健康的威胁也更大。目前，我国的医疗技术不断发展，治疗CAP也有了新的成效，通过各种抗菌药物的使用，各种致病菌均得到了有效清除[2]。不过，随着治疗时间的延长，患者对抗菌药物也会产生相应的耐药性，而CAP的治疗难度也会随之提升，因此，还需选择更为有效的治疗方案，以便致病菌的有效清除。莫西沙星便为CAP治疗中的常见药，但对于患有基础疾病的患者或老年人来说单一使用后的疗效欠佳，需采用联用的方案乃可实现治疗效果的提升[3]。鉴于此，本文将把头孢菌素类抗菌药物与莫西沙星联用，并分析其价值。现论述如下。