PiCCO监测技术应用在感染性休克治疗中的临床指导作用分析
2020-11-30孟莉林爱华许可徐大伟张海潮
孟莉 林爱华 许可 徐大伟 张海潮
[摘要] 目的 探讨PiCCO监测技术指导治疗感染性休克的临床价值。方法 便利选择2016年1月—2019年12月该院重症医学科124例感染性休克病例,随机分为实验组(PiCCO监测参数指导临床液体复苏治疗,63例)和对照组(CVP变化指导补液治疗,61例)。比较观察两组干预前及干预24 h后液体复苏相关指标及基该治疗指标,统计救治成功率。结果 实验组干预后尿量(0.44±0.07)mL/(kg·h),BLA(1.97±0.82)mmol/L,MAP(66.73±9.15)mmHg,ScvO2(69.58±9.13)%,PaO2/FiO2(286.42±30.13),液体总入量(2 875±360)mL,总液体复苏时间(96.75±22.14)h,早期复苏达标时间(5.2±1.9)h,机械通气时间(90.36±11.54)h,ICU留置时间(7.86±2.05)d,救治成功率82.54%,各项指标均优于对照组,差异有统计学意义(t=3.295、3.776、4.512、4.380、6.871、9.551、7.219、3.726、8.514、3.956,χ2=4.803,P<0.05)。結论 PiCCO监测能够准确反映血容量状态,以此指导感染性休克液体复苏治疗效果确切,可以更好地改善患者心肺功能,同时避免过度输液,有效提高救治成功率,促进早期康复。
[关键词] 感染性休克;液体复苏;PiCCO监测技术
[中图分类号] R631 [文献标识码] A [文章编号] 1674-0742(2020)09(c)-0062-03
[Abstract] Objective To explore the clinical value of PiCCO monitoring technology to guide the treatment of septic shock. Methods From January 2016 to December 2019, 124 cases of septic shock in the Department of Critical Care Medicine of the hospital were convenienty selected and randomly divided into experimental group (PiCCO monitoring parameters to guide clinical fluid resuscitation treatment, 63 cases) and control group (CVP changes guide fluid therapy, 61 cases). Comparing and observing the related indexes and basic treatment indexes of fluid resuscitation before intervention and 24 h after intervention in the two groups, and statistical treatment success rate. Results The urine output of the experimental group after intervention was (0.44±0.07) mL/(kg·h), BLA(1.97±0.82)mmol/L, MAP(66.73±9.15)mmHg, ScvO2(69.58±9.13)%, PaO2/FiO2(286.42±30.13), total amount of liquid (2 875±360)mL,total fluid resuscitation time (96.75±22.14)h, early resuscitation up to standard time (5.2±1.9)h, mechanical ventilation time (90.36±11.54)h, ICU indwelling time (7.86±2.05)d, treatment success rate 82.54%, all indicators were better than the control group, the difference was statistically significant(t=3.295,3.776,4.512,4.380,6.871,9.551,7.219,3.726,8.514,3.956,χ2=4.803,P<0.05). Conclusion PiCCO monitoring can accurately reflect the blood volume status, which can guide the exact effect of fluid resuscitation in septic shock, which can better improve the cardiopulmonary function of patients, while avoiding excessive fluid infusion, and effectively improve treatment success rate and early recovery.
[Key words] Septic shock; Fluid resuscitation; PiCCO monitoring technology
感染性休克指病原微生物及其毒素产物直接或间接引起微循环功能紊乱与组织灌注不足,导致细胞代谢与脏器功能障碍的循环衰竭综合征,是重症医学科常见急危重症[1]。该病多见于免疫功能低下、医院内感染、大手术后及严重外伤者,病理病机复杂,致死率高,是ICU危重患者死亡主要原因。临床救治该病,早期液体复苏是关键,离不开有效的血流动力学监测为其提供依据和指导[2]。脉搏分析连续心排量监测(PiCCO)是基于经肺热稀释技术和脉搏波型轮廓分析计数发展而来的一种血流动力学参数监测与容量管理技术,具有精确、简便、微创、高效费比的技术特点和优势,可用以连续动态监测血流动力学变化,评估心脏收缩功能,为液体复苏治疗提供准确指导[3]。便利选择于2016年1月—2019年12月该院124例感染性休克病例,分析探讨PiCCO在该病临床治疗中的指导作用,现报道如下。