脑膜黑色素细胞瘤
2017-11-22阎晓玲
·临床医学图像·
脑膜黑色素细胞瘤
图1 光学显微镜观察所见 HE染色 1a“编织”状间质内可见巢片状富含黑色素的梭形肿瘤细胞 ×200 1b 肿瘤细胞胞核呈椭圆形或豆形,核仁可见、呈嗜酸性 ×400Figure 1 Optical microscopy findings HE staining Spindle tumor cells rich in melanin were arranged in nests within"braided"mesenchyma(Panel 1a). ×200 The nuclei of tumor cells were oval or bean⁃shaped,with eosinophilic nucleoli(Panel 1b). ×400
脑膜黑色素细胞瘤是一种源于软脑膜黑色素细胞,组织学形态分化良好,呈实性、非浸润性的黑色素细胞瘤,是一种孤立性、不伴周围组织浸润的低级别肿瘤。组织学形态特征性表现为上皮样、纺锤形、多形或梭形黑色素细胞,无间变、坏死,核分裂象少见;梭形或椭圆形肿瘤细胞内含有数目不等的黑色素,呈紧密巢状,类似脑膜瘤“漩涡”样结构(图1a),边缘可见富含黑色素的肿瘤细胞和巨噬细胞;胞核呈椭圆形或豆形,偶见核沟,核仁可见、呈嗜酸性(图1b)。偶可见肿瘤复发。
(天津市环湖医院病理科阎晓玲供稿)
Meningeal melanocytoma
YAN Xiao⁃ling
Department of Pathology,Tianjin Huanhu Hospital,Tianjin 300350,China(Email:ll934065@126.com)
10.3969/j.issn.1672⁃6731.2017.06.015