探讨激光光凝术治疗糖尿病视网膜病变的临床疗效
2020-07-01吴伟琳
吴伟琳
【摘要】 目的 评价糖尿病视网膜病变采用激光光凝术治疗的临床效果。方法 94例糖尿病视网膜病变患者, 随机分为实验组和对照组, 每组47例。对照组患者采用内科基础治疗, 实验组患者在对照组的治疗基础上联合激光光凝术治疗。比较两组患者临床疗效以及治疗前后临床指标[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、红细胞压积、糖化血红蛋白(HbA1c)、全血粘度]水平。结果 实验组患者治疗总有效率89.36%高于对照组的61.70%, 差异具有统计学意义(P<0.05)。治疗后, 两组患者FBG、2 h PG、红细胞压积、HbA1c、全血粘度水平均优于本组治疗前, 差异具有统计学意义(P<0.05);但两组比较, 差异无统计学意义(P>0.05)。结论 激光光凝术在糖尿病视网膜病变患者中具有良好的应用效果, 能够有效改善患者的视力水平, 值得推广。
【关键词】 糖尿病视网膜病变;激光光凝术;临床疗效
DOI:10.14163/j.cnki.11-5547/r.2020.15.012
Clinical effect of laser photocoagulation on diabetic retinopathy WU Wei-lin. Dalian Fifth Peoples Hospital, Dalian 116001, China
【Abstract】 Objective To evaluate the clinical effect of laser photocoagulation on diabetic retinopathy. Methods A total of 94 diabetic retinopathy patients were randomly divided into experimental group and control group, with 47 cases in each group. The control group received by basic medical therapy, and the experimental group received laser photocoagulation on the basis of the control group. The clinical effect, and clinical indexes [fasting blood glucose (FBG), 2 h postprandial glucose (2 h PG), hematocrit, glycosylated hemoglobin (HbA1c), whole blood viscosity] before and after treatment were compared between the two groups. Results The total effective rate of treatment 89.36% of the experimental group was higher than that of the control group 61.70%, and the difference was statistically significant (P<0.05). After treatment, FBG, 2 h PG, hematocrit, HbA1c, whole blood viscosity of the two groups were better than those before treatment, and the difference was statistically significant (P<0.05). But there was no statistically significant between the two groups (P>0.05). Conclusion Laser photocoagulation has a good application effect in diabetic retinopathy patients, which can effectively improve the vision level of patients. It is worth promoting.
【Key words】 Diabetic retinopathy; Laser photocoagulation; Clinical effect
临床治疗糖尿病视网膜病变的常用方法有药物、冷凝、激光、玻璃体切割术等手段, 药物主要是为了控制血糖, 但不能从根本上改善视力水平[1], 激光光凝术是目前针对糖尿病视网膜病变患者应用最为广泛的一种技术[2, 3]。本院在对患者进行常规用药的基础上联合激光光凝术治疗, 取得了良好的临床效果, 现报告如下。
1 资料与方法
1. 1 一般资料 选取2018年5月~2019年8月本院收治的94例糖尿病视网膜病变患者, 所有患者均符合《實用眼科学》中提到的相关诊断标准[2], 单眼发病, 自愿签署知情同意书, 眼底检查发现患者伴有出血、黄斑水肿、硬性渗出等表现。排除妊娠哺乳期女性、合并其他眼科疾病、对研究药物过敏、肝肾功能异常、最近3个月内接受过相关治疗的患者。将所有患者随机分为实验组和对照组, 每组47例。实验组男27例, 女20例;年龄45~78岁, 平均年龄(60.72±5.77)岁;左眼发病18例, 右眼发病29例;糖尿病病程3~27年, 平均糖尿病病程(16.28±4.43)年;合并症:27例高血