支气管肺泡灌洗对肺脓肿及支气管扩张合并感染患者肺功能的影响
2019-04-10涂智毅杨志明何涛邹天士
涂智毅 杨志明 何涛 邹天士
[摘要]目的 研究支气管肺泡灌洗对肺脓肿及支气管扩张合并感染患者肺功能的影响。方法 选取2017年1月~2018年1月我院收治的84例肺膿肿及支气管扩张合并感染患者作为研究对象,采用随机分组方法分为对照组(42例)与实验组(42例)。对照组患者接受常规药物治疗,实验组患者接受支气管肺泡灌洗治疗,比较两组患者治疗后的肺功能、治疗效果和不良反应。结果 治疗后,实验组患者的用气呼吸量(FVC)、一秒钟最大呼气量(FEV1)、最大呼气流量(PEF)高于对照组患者,差异有统计学意义(P<0.05)。实验组患者的治疗总有效率高于对照组患者,差异有统计学意义(P<0.05)。实验组的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论 肺脓肿和支气管扩张合并感染患者接受支气管肺泡灌洗治疗,能够有效改善患者的肺部功能,值得推广应用。
[关键词]肺脓肿;支气管扩张;感染;支气管肺泡灌洗;肺功能
[中图分类号] R562.2+2 [文献标识码] A [文章编号] 1674-4721(2019)2(c)-0078-03
[Abstract] Objective To study the influence of bronchoalveolar lavage on pulmonary function in patients with pulmonary abscess and bronchiectasis complicated with infection. Methods A total of 84 patients with pulmonary abscess and bronchiectasis complicated infection who were admitted to our hospital from January 2017 to January 2018 were selected as the research objects. The patients were divided into the control group (42 cases) and the experimental group (42 cases) by randomized method. Patients in the control group received conventional drug therapy, and patients in the experimental group received bronchoalveolar lavage. The lung function, treatment effect and adverse reactions of the two groups were compared. Results After treatment, the level of breathing volume (FVC), maximum expiratory volume in one second (FEV1), maximum expiratory flow (PEF) of the experimental group were higher than those of the control group, the difference was statistically significant (P<0.05). The total effective rate of the experimental group was higher than that of the control group, the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the experimental group was lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion Patients with pulmonary abscess and bronchiectasis combined with bronchoalveolar lavage can effectively improve the lung function of patients, which is worthy of popularization and application.
[Key words] Lung abscess; Bronchiectasis; Infection; Bronchoalveolar lavage; Pulmonary function
肺脓肿和支气管扩张合并感染是临床上常见的呼吸系统疾病,此病在临床上具有较高的发病率,且患者发病后,病情较为严重,对患者的危害较大[1]。肺脓肿及支气管扩张合并感染会对患者的肺部功能造成严重损伤,能够引发患者出现气胸、胸闷、气喘、呼吸困难和呼吸衰竭的症状,且合并感染会对患者的多处器官造成伤害,严重危及患者的身体健康,因此需要对患者进行及时有效的治疗,以改善患者的肺部功能,提升患者的生存质量[2]。本研究主要研究支气管肺泡灌洗对肺脓肿及支气管扩张合并感染患者肺功能的影响,现报道如下。
1资料与方法
1.1一般资料
选取2017年1月~2018年1月在我院接受治疗的84例肺脓肿及支气管扩张合并感染患者作为研究对象,根据患者接受治疗方法的不同分为对照组与实验组,各42例。对照组中,男26例,女16例;年龄为43~74岁,平均(58.43±5.26)岁;其中肺脓肿患者20例,支气管扩张合并感染患者22例。实验组中,男27例,女15例;年龄为44~75岁,平均(59.47±5.30)岁;其中肺脓肿患者21例,支气管扩张合并感染患者21例。纳入标准:所有患者均确诊为肺脓肿及支气管扩张合并感染;所有患者均无治疗禁忌证[3]。排除标准:伴有严重心、肝、肺等严重器质性的患者;伴有严重精神疾病和认知障碍的患者[4]。所有患者均知情,并自愿接受相关治疗和研究,患者自愿签订知情同意书,两组患者的一般资料比较,差异无统计学意义(P>0.05),具有可比性。