实施胰十二指肠切除术治疗胰腺癌患者的临床效果分析

陈伟　孙诚谊

[摘要] 目的 探討实施胰十二指肠切除术治疗胰腺癌患者的临床效果观察。方法 方便2015年10月—2017年4月在该院外科治疗的50例胰腺癌患者随机分为两组，每组25例，对照组采用标准胰十二指肠切除术治疗，观察组采用扩大胰十二指肠切除术治疗，比较两组患者的各项手术指标、并发症发生率。结果 观察组在手术时间、淋巴结清扫总数量分别为（297.82±82.75）min、（11.81±6.14）个，与对照组相比差异有统计学意义（P<0.05）；术中出血量、阳性淋巴结清扫数量、住院时间两组相比，观察组分别为（792.47±44.58）mL、（1.52±0.46）个、（34.25±4.29）d，对照组分别为（802.31±47.52）mL、（1.23±0.42）个、（35.31±6.74）d，差异无统计学意义（P>0.05）；观察组术后并发症发生率20.00%与对照组28.00%相比差异无统计学意义（P>0.05）。结论 胰十二指肠切除术治疗胰腺癌效果确切，临床可根据患者的实际情况选择标准或扩大术式，以获得最佳疗效。

[关键词] 胰腺癌；胰十二指肠切除术；临床效果

[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742（2018）02（c）-0090-03

Clinical Effect Analysis of Applying Pancreaticoduodenectomy in the Treatment of Pancreatic Cancer

CHEN Wei1，SUN Cheng-yi2

1.Department of Clinic， Guizhou Medical University， Guiyang， Guizhou Province，550004 China； 2.Department of Hepatobiliary Surgery， Affiliated Hospital of Guizhou Medical University， Guiyang， Guizhou Province， 550004 China

[Abstract] Objective This paper is to investigate the clinical effect of pancreaticoduodenectomy treatment of pancreatic cancer patients. Methods 50 patients with pancreatic cancer in this hospital from October 2015 to April 2017 were convenient selected and randomly divided into two groups， each group contained 25 patients. Control group adopted standard pancreaticoduodenectomy in the treatment while the observation group adopted extended pancreatoduodenectomy. Then compared the operation index and rate of complications between the two groups. Results The operation duration and total number of lymph node dissection were respectively （297.82 ± 82.75） min and （11.81 ± 6.14）， which were obviously different with those of the observation group（P<0.05）； as for the bleeding volume， number of positive lymph node dissection and hospitalization duration in the observation group were respectively（792.47±44.58）mL， （1.52 ± 0.46）， （34.25± 4.29） d while those of the control group were respectively （802.31 ± 47.52）mL， （1.23 ± 0.42）， （35.31 ± 6.74） d. The difference had no statistical significance（P>0.05）. The rate of complication in the observation group was 20.00%， which had no obvious difference with that of the control group of 28.00%.（P>0.05） Conclusion Pancreaticoduodenectomy is effective in the treatment of pancreatic cancer. Standard or expand pancreaticoduodenectomy can be applied in clinical treatment on the basis of the actual situations of patients to obtain the best effect.

[Key words] Pancreatic cancer； Pancreatoduodenectomy； Clinical effect.