CT与MRI诊断原发性肝癌介入术后病灶残留及复发临床价值
2020-05-11徐庆邓凡潘海松
徐庆 邓凡 潘海松
【摘要】 目的:研究CT和MRI对原发性肝癌介入治疗后病灶残留及复发的诊断价值。方法:纳入90例患者作为此次研究的对象,纳入时间段为2018年3月-2019年1月,所有患者均在笔者所在医院确诊为原发性肝癌,均在笔者所在医院接受了介入术治疗,治疗6个月后对患者进行随访,分别对90例患者进行DSA(数字减影血管造影)检查、CT检查、MRI检查,以DSA检查结果作为此次研究的对照标准,分别将CT、MRI检查的结果与DSA的检查结果进行对比,评价CT、MRI對此类患者的诊断效果。结果:DSA检查54例(60.00%)患者存在病灶残留,42例(46.67%)患者出现复发。CT检查42例(46.67%)存在病灶残留(准确率、特异性、灵敏度分别为86.67%、100%、77.78%),35例(38.89%)出现复发(准确率、特异性、灵敏度分别为92.22%、100%、83.33%);MRI检查50例(55.56%)存在病灶残留(准确率、特异性、灵敏度分别为95.56%、100%、92.59%),41例(45.56%)出现复发(准确率、特异性、灵敏度分别为98.89%、100%、97.62);CT与MRI对病灶残留及复发诊断的特异性差异无统计学意义(P>0.05),但MRI对病灶残留及复发诊断的准确率及灵敏度均显著高于CT(P<0.05)。结论:对原发性肝癌介入治疗后病灶残留及复发的诊断工作来说,MRI较CT有着更高的利用价值,对于病灶残留及复发诊断的准确率及灵敏度显著高于CT,因此,值得在临床上进行推广及应用。
【关键词】 MRI CT 原发性肝癌 介入治疗 病灶残留 复发诊断
doi:10.14033/j.cnki.cfmr.2020.02.029 文献标识码 B 文章编号 1674-6805(2020)02-00-03
[Abstract] Objective: To study the diagnostic value of CT and MRI in residual and recurrence of primary hepatic cancer after interventional therapy. Method: Ninety patients were included in this study. They were diagnosed as primary hepatic carcinoma in our hospital from March 2018 to January 2019. All patients received interventional therapy in our hospital. After six months of treatment, the patients were followed up and 90 patients underwent DSA (digital subtraction angiography) examination, CT and MRI, DSA was used as the control criteria for this study. The results of CT and MRI were compared with those of DSA, and the diagnostic effects of CT and MRI were evaluated. Result: DSA results showed that 54 patients (60.00%) had residual lesions and 42 patients (46.67%) had recurrence. CT results showed that 42 patients (46.67%) had residual lesions (accuracy, specificity and sensitivity were 86.67%, 100%, 77.78%, respectively), and 35 patients (38.89%) had recurrence (accuracy, specificity and sensitivity were 92.22%, 100%, 83.33%). The results of MRI showed that 50 cases (55.56%) had residual lesions (accuracy, specificity and sensitivity were 95.56%, 100% and 92.59%, respectively), and 41 cases (45.56%) had recurrence (accuracy, specificity and sensitivity were 98.89%, 100% and 97.62% respectively). There was no statistical difference in the specificity of CT and MRI in diagnosis of residual and recurrent lesions (P>0.05), but the accuracy and sensitivity of MRI in diagnosis of residual and recurrent lesions were significantly higher than those of CT (P<0.05). Conclusion: For the diagnosis of residual and recurrence of primary hepatic carcinoma after interventional therapy, MRI is more valuable than CT. The accuracy and sensitivity of diagnosis of residual and recurrence of primary hepatic carcinoma are significantly higher than CT. Therefore, it is worth popularizing and applying in clinic.
MRI扫描技术是在磁共振成像原理的基础上使用的,可以对人体的各个器官、阻滞进行扫描检查。众所周知,人体是存在磁敏感差异的,磁敏感性与磁敏感物质可以在此种差异的基础上构成图像,利用磁敏感性与人体的磁敏感差异的图像特征,在临床上可以有效诊断多种疾病,而利用磁敏感物质与人体的磁敏感差异的图像特征,可以有效检测出一些磁性物质,该方法提供了更加便捷、准确的技术支持,为广大患者提供了更加安全、有效、可靠的服务[9]。
本次研究中,纳入了90例接受介入治疗的原发性肝癌患者作为研究对象,在患者接受介入治疗6个月后,以DSA检查作为此次研究的金标准,对患者分别进行CT、MRI检查,将CT、MRI检查的病灶残留、复发的结果与DSA进行对比,研究结果显示,CT与MRI对病灶残留及复发诊断的特异性差异无统计学意义(P>0.05),但MRI对病灶残留及复发诊断的准确度及灵敏度均显著高于CT(P<0.05)。分析原因可能是:因为CT检查的方法主要是反映患者肝部血流动力学的情况,但大部分患者合并患有肝硬化,而肝硬化会导致患者肝部血流动力学情况发生改变,因此导致诊断效果降低,而MRI主要是反映解剖结构的信号,因此诊断效果较好[10]。
综上所述,对原发性肝癌介入治疗后病灶残留及复发的诊断工作来说,MRI较CT有着更高的利用价值,对于病灶残留及复发诊断的准确率及灵敏度显著高于CT,因此,值得在临床上进行推广及应用。
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(收稿日期:2019-09-04) (本文编辑:何玉勤)