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六味地黄丸联合消渴丸治疗2型糖尿病临床分析

2019-11-12尹艳飞

糖尿病新世界 2019年16期
关键词:六味地黄医治学报

尹艳飞

[摘要] 目的 探究六味地黄丸联合消渴丸治疗2型糖尿病临床效果。 方法 将2018年1—12月该院治疗的2型糖尿病患者86例纳入研究,将之分为两组,每组43例,对照组给予消渴丸治疗,观察组给予六味地黄丸联合消渴丸进行医治,医治结束后比较两组医治疗效。 结果 经积极医治后,两组的FPG、2 hPG、HbAlc指标水平均降低,但观察组降低程度大于對照组,在治疗总有效率上,观察组为95.35%,高于对照组的76.74%,两组数据差异有统计学意义(P<0.05)。结论 六味地黄丸联合消渴丸治疗2型糖尿病,降糖效果显著,值得采纳应用。

[关键词] 六味地黄丸;消渴丸;2型糖尿病;临床效果

[中图分类号] R28          [文献标识码] A          [文章编号] 1672-4062(2019)08(b)-0075-02

[Abstract] Objective To investigate the clinical effect of Liuwei Dihuang Pill combined with Xiaoke Pill in the treatment of type 2 diabetes mellitus. Methods 86 patients with type 2 diabetes mellitus treated in our hospital from January to December 2018 were enrolled in the study. They were divided into two groups, 43 cases in each group. The control group was given Xiaoke Pills. The observation group was given Liuwei Dihuang Pills. The joint Xiaoke Pills was used for treatment, and the therapeutic effects of the two groups were compared after the treatment. Results After active treatment, the levels of FPG, 2 hPG and HbAlc in the two groups decreased, but the decrease in the observation group was greater than that in the control group. In the total effective rate of treatment, the observation group was 95.35%, which was higher than the control group of 76.74%, and the data were significantly different (P<0.05), which was statistically significant. Conclusion Liuwei Dihuang Pill combined with Xiaoke Pill in the treatment of type 2 diabetes has significant hypoglycemic effect and is worthy of adoption.

[Key words] Liuwei Dihuang Pill; Xiaoke Pill; Type 2 diabetes; Clinical effect

显差异;ER、RR、HER2、Ki-67表达情况可为乳腺癌预后的判断、临床治疗方案的制定提供帮助,但两组数据对比差异不大;观察组患者的5年生存率更低,说明合并2型糖尿病的乳腺癌患者的预后效果更差,分析原因在于,糖尿病在合并2型糖尿病的乳腺癌患者治疗中会对临床疗效产生不良影响,因此导致预后效果不如单纯乳腺癌患者,另外糖尿病患者存在高胰岛素血症,会增加IGF合成量及活性[5],参与了肿瘤的浸润、转移过程[6-7],因此合并2型糖尿病的乳腺癌患者存在较高的复发转移率,提示糖尿病是影响乳腺癌患者疗效和预后的重要因素。

综上所述,合并2型糖尿病的乳腺癌患者具有更高的组织学分级,发生三阴性乳腺癌的风险更高,且预后效果不如乳腺癌患者。

[参考文献]

[1]  何唐艳.合并2型糖尿病的激素依赖型乳腺癌患者的临床特点及预后[D].广西:广西医科大学,2017.

[2]  田晓菲,李碧丽.合并2型糖尿病乳腺癌患者的临床病理特征分析[J].现代医学,2017,45(2):239-243.

[3]  王海燕,权毅.合并2型糖尿病的乳腺癌的临床病理特征及预后研究[J].泸州医学院学报,2016,39(5):446-450.

[4]  曹敏.乳腺癌合并2型糖尿病患者的临床特征及预后[J].中国卫生标准管理,2016,7(22):15-17.

[5]  康世瑾,安淑敏,刘志远,等.合并2型糖尿病的乳腺癌的临床病理特征及预后研究[J].糖尿病新世界,2016,19(6):59-60.

[6]  刘桂红,周卫华,张玉娜,等.乳腺癌合并2型糖尿病患者的临床病理特征及预后分析[J].河北医科大学学报,2016,37(3):249-251,255.

[7]  李丽慧,高宇,陈海兰,等.乳腺癌合并2型糖尿病患者临床病理特征分析[J].承德医学院学报,2015,32(2):126-128.

(收稿日期:2019-05-21)

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