宫腹腔镜联合辅助生殖技术治疗输卵管性不孕临床研究

丁娇 邵军晖 杨琳

摘 要 目的：探讨宫腹腔镜联合辅助生殖技术治疗输卵管性不孕的临床疗效。方法：将2015年12月至2017年12月接诊的输卵管性不孕患者60例随机分为观察组和对照组各30例。对照组采用宫腹腔镜手术治疗，观察组在对照组治疗的基础上联合辅助生殖技术治疗。观察患者输卵管梗阻、再疏通、并发症发生及妊娠情况。结果：两组输卵管梗阻、再疏通及并发症发生率差异无统计学意义（P>0.05）。观察组1年妊娠19例（63.33%），2年妊娠25例（83.33%），对照组分别为11例（36.67%）和17例（56.67%），组间差异有统计学意义（P<0.05）。结论：宫腹腔镜联合辅助生殖技术治疗输卵管性不孕对患者的输卵管梗阻及再疏通情况影响较小，未增加患者的并发症发生情况，但患者的1、2年妊娠率明显提高，應用价值较高。

关键词 输卵管性不孕；宫腹腔镜；辅助生殖技术

中图分类号：R711.6 文献标志码：A 文章编号：1006-1533（2019）06-0022-02

Clinical study of hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility

DING Jiao， SHAO Junhui， YANG Lin（Assisted Reproductive Department of Maternal and Child Health Care Center of Xinyu， Xinyu 338000， Jiangxi Province， China）

ABSTRACT Objective： To explore the clinical efficacy of hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility. Methods： Sixty patients with tubal infertility who were admitted from December 2015 to December 2017 were randomly divided into an observation group and a control group with 30 cases in each group. The control group was treated with laparoscopic surgery， and the observation group was combined with assisted reproductive technology treatment based on the treatment of the control group. The patients fallopian tube obstruction， recanalization， complications and pregnancy were observed. Results： There were no significant differences in the incidence of tubal obstruction， recanalization and complication between the two groups（P>0.05）. In the observation group， 19 cases（63.33%） were pregnant in 1 year， 25 cases（83.33%） in 2 years of pregnancy， and in the control group， 11 cases（36.67%） and 17 cases（56.67%）， and the difference between the groups was statistically significant（P<0.05）. Conclusion： Hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility has less influence on the tubal obstruction and recanalization， and do not increase the patients complications， but the pregnancy rate of the patients is significantly improved in 1 and 2 years， and the application value is higher.

KEY WORDS tubal infertility； hysteroscopy-laparoscopy； assisted reproductive technology

输卵管性不孕症影响夫妻和谐、家庭幸福。输卵管具有运送精子、拾取卵子及把受精卵运送到子宫腔的重要作用，输卵管不通或功能障碍是造成女性不孕症的主要原因[1-2]。造成输卵管不通或功能障碍的原因是急、慢性输卵管炎症。随着微创技术的发展，宫腹腔镜技术不断成熟，并在妇科广泛应用[3-4]。采用宫腹腔镜治疗创伤小、术后易恢复，优势明显[5]。本文报道采用宫腹腔镜联合辅助生殖技术治疗输卵管性不孕的疗效。

1 资料与方法

1.1 一般资料