上海市某疗养院体检人群体重指数与血脂水平及非酒精性脂肪肝关系的调查研究

吴玉梅

[摘要] 目的 探討某疗养院体检人群体重指数与血脂水平及非酒精性脂肪肝关系。 方法 选择我院进行体检的人群共10245例为研究对象，根据BMI结果分为<18.5 kg/m2组（A组）179例，18.5～23.9 kg/m2组（B组）3923例，24.0～27.9 kg/m2组（C组）4650例，≥28.0 kg/m2组（D组）1493例，比较不同BMI分组者高TG血症、高TC血症、混合型高脂血症以及非酒精性脂肪肝发生率。 结果 不同BMI分组TC、TG、HDL-C、LDL-C水平比较，差异有统计学意义（P<0.01）；其中B组、C组及D组TC、TG、LDL-C水平显著高于A组，C组、D组TC、TG、LDL-C水平显著高于B组，D组TC、TG、LDL-C水平显著高于C组，差异均有统计学意义（P<0.01）；B组、C组及D组HDL-C显著低于A组，C组、D组HDL-C水平显著低于B组，D组HDL-C显著低于C组，差异均有统计学意义（P<0.01）。不同BMI分组者高TC血症、高TG血症、混合型高脂血症、非酒精性脂肪肝发生率比较，差异有统计学意义（P<0.01）；不同BMI分组者高TC血症、高TG血症、混合型高脂血症、非酒精性脂肪肝发生率比较，差异有统计学意义（P<0.01）；其中D组发病率最高，其次为C组、B组，A组发病率最低。 结论 健康体检人群体重指数越高，高脂血症、非酒精性脂肪肝发生率越高。

[关键词] 健康体检人群；体重指数；血脂水平；非酒精性脂肪肝

[中图分类号] R575.5 [文献标识码] B [文章编号] 1673-9701（2017）30-0121-03

[Abstract] Objective To investigate the relationship between body mass index and blood lipid level， nonalcoholic fatty liver of physical examination population in a sanatorium. Methods A total of 10245 patients who underwent physical examination in our hospital were selected as the study subjects. According to the BMI results， the patients were divided into <18.5 kg/m2 group （group A， n=179）， 18.5-23.9 kg/m2 group （group B， n=3923）， 24.0-27.9 kg/m2 group （group C， n=4650） and ≥28.0 kg/m2 group（group D， n=1493）. The incidence rates of hyperglycemia， hyperlipidemia， mixed hyperlipidemia and nonalcoholic fatty liver disease among different BMI groups were compared. Results There were significant differences in the levels of TC， TG， HDL-C and LDL-C in different BMI groups（P<0.01）. The levels of TC， TG and LDL-C in group B， group C and group D were significantly higher than those in group A. The levels of TC， TG and LDL-C in group C and group D were significantly higher than those in the group A， and the levels of TC， TG and LDL-C in group D were significantly higher than those in the group C. And the difference was significant （P<0.01）. The HDL-C in group B， group C and group D was significantly lower than that in group A， and the HDL-C of group C and group D was significantly lower than that in group B， and the HDL-C in group D was significantly lower than that in group C. The difference was statistically significant（P<0.01）. There were significant differences in the incidences of hyperlipidemia， hyperglycemia， mixed hyperlipidemia and nonalcoholic fatty liver disease in different BMI groups（P<0.01）. The incidence of D group was the highest， followed by group C， group B， and group A had the lowest incidence. Conclusion The higher the body mass index of the healthy physical examination population， the higher the incidence of hyperlipidemia and nonalcoholic fatty liver disease.endprint