2 Acupuncture and Moxibustion

2 Acupuncture and Moxibustion

2015135 Clinical observation on delayed encephalopathy after carbon monoxide poisoning treated with acupuncture to restore consciousness combined with hyperbaric oxygen treatment.MAO Min（茅敏），et al. Neurol Med Dept，Chengdu 1st People's Hosp，Chengdu 610041.Chin Acupunct&Moxibust 2015；35（3）：213-216.

Objective To compare the efficacy differences on delayed encephalopathy after carbon monoxide poisoning （DEACMP）between acupuncture to restore consciousness combined with hyperbaric oxygen treatment and simply hyperbaric oxygen treatment.Methods Forty-one patients with DEACMP were randomly divided into an observation group（21 cases）and a control group（20 cases）.In the observation group，acupuncture was applied at Neiguan（PC 6），Shuigou（GV 26），Baihui（GV 20），Sishencong（EX-HN 1），Fengchi（GB 20），Hegu（LI 4），Sanyinjiao（SP 6）and Taichong（LR 3），and hyperbaric oxygen treatment was given as well.In the control group，simple hyperbaric oxygen treatment was used.The treatment was adopted once every day，and continuous 5 days'treatment made one session in the two groups. There were two days at the interval between two sessions and 6 sessions in the two groups.The changes of scores of mini mental state examination（MMSE）and Barthel index（BI）for activity of daily life and routine electroencephalogram（EEG）before and after treatment were compared.Results After treatment，the scores of MMSE and BI and EEG were all improved compared with those before treatment（all P＜0.01）.The raise of the scores of MMSE and BI in the observation group was more obvious than that in the control group（both P＜0.05）and the improvement of EEG abnormal condition in the observation group was also superior to that in the control group after treatment（P＜0.05）.Conclusion Acupuncture to restore consciousness combined with hyperbaric oxygen could obviously improve the cognitive function，activity of daily life and changes of EEG，and it is better than simply hyperbaric oxygen treatment.

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2015136 Effect of acupuncture and moxibustion on depressive states of stroke patients'spouses.WANG Chengwei（王成伟），et al.Dept Integr West&Chin Med，WestChinaHosp，SichuanUniv，Chengdu 610041.Chin Acupunct&Moxibust 2015；35（3）：223-226.

Objective To verify the clinical efficacy of acupuncture and moxibustion on depressive states of stroke patients'spouses.Methods According to inclusive criteria，forty-four stroke patients'spouses with mild or moderate depressive states were randomly divided into an acupuncture-moxibustion group and a blank control group，22 cases in each group.In the acupuncture-moxibustion group，acupuncture was applied at Baihui（GV 20），Shenting（GV 24），Sishencong（EX-HN 1），Hegu（LI 4），Zhsanli（ST 36）and Taichong（LR 3），and suspended moxibustion was used at Shenque（CV 8），Guanyuan （CV 4）and Zhongwan（CV 12）.The treatment was given twice a week for continuous 8 weeks.In the blank control group，neither acupuncture nor moxibustion treatment was given，and the patients were only treated with healthy and psychological guidance.Before and after 8-week treatment，scores of self-rating depression scale （SDS）and insomnia severity grade were observed. Results In the two groups，the scores of SDS were both reduced than those before treatment（both P＜0.05），and the decrease in the acupuncture-moxibustion group was more obvious（P＜0.05）.After treatment，the number of insomnia severity grade in the acupuncture-moxibustion group was improved than that before treatment （P＜0.001），and the improvement was evidently superior to that in the blank control group（P＜0.05）.The numbers of insomnia severity grade of the blank control group before and after treatment had no statistic significance（P＞0.05）.Conclusion The acupuncture andmoxibustion intervention plan has clinical treatment significance in the improvement of mild and moderate depressive states for the stroke patients'primary caregivers who are the spouses.

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2015137 Primary hypertension treated with acupuncture combined with auricular point sticking：a randomized controlled trial.YANG Xiaolin（杨晓琳），et al.Dept TCM，2nd Hosp，Tianjin Med Univ，Tianjin 300211.Chin Acupunct&Moxibust 2015；35（3）：227-231.

Objective To compare clinical effects between acupuncture combined with auricular point sticking and western medicine on primary hypertension.Methods Ninety patients with primary hypertension were randomly divided into a medication group and a combination group，45 cases in each group.In the medication group，captopril tablets were treated with oral administration，12.5 mg each time，twice a day；in the combination group，acupuncture and auricular point sticking were used，and acupuncture was applied at Renying（ST 9），Fengchi（GB 20）and Baihui（GV 20），while auricular point sticking was adopted at Shenmen（TF4），Xin （CO15），Jiangyagou and Jiaogan（AH6a），once a day for continuous 4 weeks.After treatment，the changes of 24 h ambulatory blood pressure，angiotensinⅡ（AngⅡ）level，creatinine level and syndrome scores were observed and the clinical efficacy was assessed in the two groups. Results After 4 weeks'treatment，24 h ambulatory blood pressure was improved compared with that before treatment in the two groups（P＜0.01，P＜0.05）.The reducing of 24 h ambulatory blood pressure in the combination group was superior to that in the medication group （P＜0.05）.There were reducing tendencies of coefficients of variation（CVs）of the two groups，and in the combination group，the CVs of 24 h ambulatory blood pressure and systolic pressure acquired more obvious reducing range compared with the medication group（both P＜0.05）.Serum AngⅡ level and plasma creatinine level of the patients in the two groups after treatment were both decreased（both P＜0.05）and the reducing of AngⅡ level and creatinine level of the combination group was more obvious than that of the medication group （both P＜0.05）.The syndrome scores of the two groups after treatment were both remarkably decreased（both P＜0.05），and the reducing of the syndrome scores of the combination group was more marked than that of the medication group（P＜0.05）.The total effective rate of the combination group was 95.6%（43/45），which was superior to 71.1%（32/45）of the medication group（P＜0.05）. Conclusion Acupuncture combined with auricular point sticking for primary hypertension has reliable effect.It is better than captopril for the improvement of 24 h ambulatory blood pressure，AngⅡ level and creatinine level，and can improve dizzy，palpitation and other clinical symptoms.

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2015138 Clinical observation of auricular point sticking combined with western medicine for preventing and treating postoperative complications of external excision and internal ligation on mixed hemorrhoid.LONG Qing（龙庆），et al.Dept TCM，Affil Hosp，Luzhou Med Coll，Luzhou 646000.Chin Acupunct&Moxibust 2015；35（3）：237-240.

Objective To explore the effect of auricular point sticking before operation for postoperative complications of external excision and internal ligation on mixed hemorrhoid.Methods Eighty patients with mixed hemorrhoid were randomly divided into observation group and control group，40 cases in each group.In the control group，paracetamol and dihydrocodeine tartrate tablets were applied orally 1 h after operation，510 mg each time，twice a day；at the same time，diosmin tablets were used orally，0.9 g each time，twice a day.Three days'treatments were acquired successively.In the observation group，auricular point sticking was used before operation based on the treatment in the control group.The auricular points of Shen（CO10），Pangguang（CO9），Shenmen （TF4），Pizhixia（AT4），Jiaogan（AH6a）and Gangmen （HX5）were selected.The patients were asked to press the points 3-6 times per day，3-5 min each time，3 days'treatment in total.The scores of the pos toperativecomplications in the 1st and the 2nd days were compared between the two groups such as pain，edema，hematochezia，retention of urine，etc.Results After operation，the scores of pain，edema，hematochezia，retention of urine on the 2nd day were all decreased obviously than those in the 1st day in the two groups（all P＜0.05）；and the scores of pain，edema，hematochezia，retention of urine in the 1st and the 2nd days of the observation group were lower than those in the control group（all P＜0.05）.Conclusion Auricular point sticking before operation combined with conventional western medicine with oral administration for preventing and treating postoperative complications of external excision and internal ligation on mixed hemorrhoid achieves positive and reliable efficacy.

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2015139 Effect of electro-acupuncture at Neiguan （PC6）and Lieque（LU7）on the expression of protein kinases in cardiomyocytes of myocardial ischemia rats.WANG Ying（王颖），et al.Acupunct Faculty Clin Res，Acupunct&Massage Coll，Liaoning TCM Univ，Shenyang 110032.Chin J Integr Trad&West Med 2015；35（3）：338-342.

Objective To study the effect of electro-acupuncture （EA）at Neiguan（PC6）and Lieque（LU7）on the expression of protein kinases in cardiomyocytes of myocardial ischemia（MI）rats.Methods Healthy male SD rats were randomly divided into the control group，the model group，the Neiguan point group，the Lieque point group，and the non-meridian non-acupoint group，10 in each group using random digit table.The MI rat model was establishedbyinjectingisoprenalinehydrochloride （85 mg/kg）.EA at Neiguan（PC6），Lieque（LU7），and non-meridian non-acupoint were respectively performed.Changes of the expression of protein kinases ［such as protein kinase A（PKA），protein kinase C （PKC），protein kinase G（PKG）］in rat cardiomyocytes were observed using Western blot.Results Compared with the control group，expression levels of PKA，PKC，and PKG increased obviously in the model group（P＜0.01）.Compared with the model group，expression levels of PKA，PKC，and PKG decreased in the Neiguan point group and the Lieque point group（P＜0.01，P＜0.05）.Expression levels of PKA decreased in the nonmeridian non-acupoint group（P＜0.01）.Compared with the Neiguan point group，expression levels of PKA，PKC，and PKG increased in the non-meridian non-acupoint group and the Lieque point group（P＜0.01，P＜0.05）.Compared with the Lieque point group，expression levels of PKA，PKC，and PKG increased in the non-meridian non-acupoint group（P＜0.01，P＜0.05）. Conclusion EA at Neiguan（PC6）and Lieque（LU7）could decrease protein expression levels of PKA，PKC and PKG in rat myocardial cells，and the effect of acupuncture at Neiguan（PC6）was better than that obtained by EA at Lieque（LU7）.

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