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院士风采

2013-12-23

科技传播 2013年14期
关键词:学部委员博士学位丙氨酸

王世真

1916.03.07~

核医学家。原籍福建福州,生于日本千叶。1928年毕业于清华大学化学系。1948年和1949年在美国依阿华大学分别获化学硕士、博士学位。中国协和医科大学教授、中国医学科学院放射医学研究所名誉所长。1956年创办中国第一个同位素应用训练班。在中国创建了同位素标记物合成、液闪测量、放免分析、医用活化分析、稳定核素医学应用、放免显像等技术;系统地进行了甲状腺激素的示踪研究,对中国核医学的研究与应用起了积极的推动作用。

1980年当选为中国科学院院士(学部委员)。

Nuclear medicine specialist. Born in Chiba,Japan. Graduated from the Department of Chemistry, Tsinghua University in 1938. Received MS and Ph. D. of chemistry from University of Iowa, USA in 1948 and 1949, respectively. Professor, Peking Union Medical College, and honorary director, Institute of Radiation Medicine, Chinese Academy of Medical Sciences.

Wang set up China’s first training course on the application of isotopes in 1956, developed the synthesis of labeled compounds, liquid scintillation counting, radioimmunoassay, biomedical activation analysis, medical application of stable nuclides, radioimmuno-imaging and various isotopic techniques in China. He carried out systematic tracer research of thyroid hormones and played an initiative and promotive role for the growth of nuclear medicine in China.

He was elected Member of the Chinese Academy of Sciences in 1980.

王伏雄

1913.10.16~1995.3.11

植物学家。浙江兰溪人。1936年毕业于清华大学生物系,1941年清华大学研究员毕业,获硕士学位。1946年获美国伊利诺大学哲学博士学位。中国科学院植物研究所研究员。主要从事植物胚胎学和花粉形态学研究,特别对裸子植物胚胎学及系统演化方面有系统的研究和见解。在中国首先开创近代植物花粉形态的研究。出版了许多专著,培养了一批有成就的人才。

1980年当选为中国科学院院士(学部委员)。

Botanist. Born in Lanxi, Zhejiang Province. Graduated from the Department of Biology, Tsinghua University in 1936. Received MS from the Graduated School, Tsinghua University in 1941 and Ph.D. from Illinois University, USA in 1946. Research professor, Institute of Botany, Chinese Academy of Sciences.

Wang is mainly engaged in the study of plant embryology and pollen morphology, especially systematic research on embryology of gymnosperms and systematic evolution of gymnosperms. He obtained profound insight and understanding. He initiated the study of pollen morphology of extant plants, published a lot of monographs and brought up a great number of accomplished talents.

He was elected Member of the Chinese Academy of Sciences in 1980.

王志均

1910.08.03~2000.12.04

生理学家。山西昔阳人。1936年毕业于清华大学生物系。1950年获美国伊利诺大学医学院哲学博士学位。北京医科大学生理学教授。曾利用具有移植胰的狗,观察各种食物在小肠中引起促胰液素和促胰酶素(即胆囊收缩素)释放的情况,被认为是食物引起胃肠激素释放的定量研究的开端;阐明迷走—胰岛素系统,发现交感神经对胰高血糖素的释放作用,处于当时世界领先水平;证实了迷走—胃泌素机制在胃液分泌神经反射期中的重要意义;后发现有些胃肠激素具有细胞保护作用,提出细胞保护可能是胃肠激素的生理功能之一的假说,已获得不少证据支持。

1980年当选为中国科学院院士(学部委员)。

Physiologist. Born in Xiyang, Shaanxi Province. Graduated from the Department of Biology, Tsinghua University in 1936. Research Ph. D. from the Medical School, University of Illinois, USA in 1950. Professor, Beijing Medical University.

Wang made use of dogs with transplanted pancreas to observe the release of secretin and pancreozymin (i.e. the cholecystokinin) caused by various kinds of food in small intestine. This work was regarded as the beginning of quantitative assessment of the gastrointestinal hormonal release caused by food. He clarified the vago-insulin system and first discovered the releasing effect of the sympathetic nerve on glucagon. He confirmed the significance of vagal-gastrin mechanism in the gastric secretion of psychic phase. In recent years, he found that some gastrointestinal hormones have cytoprotective effect and proposed a hypothesis that cytoprotection might be one of the physiologic functions of gastrointestinal hormones. This hypothesis is now supported by quite a few proofs.

He was elected Member of the Chinese Academy of Sciences in 1980.

王德宝

1918.05.07~2002.11.01

生物化学家。江苏泰兴人。1940年毕业于重庆中央大学。1951年获美国西部保留地大学博士学位。1951~1954年在美国约翰·霍普金斯大学从事博士后研究。中国科学院上海生物化学研究所研究员。解决了辅酶A中第三个磷酸的位置,首创了从辅酶Ⅰ直接合成辅酶Ⅱ的大量制备方法,30年来为世界各大药厂采用;在我国最早开展了核酸生化的研究工作,是我国生产核苷酸类助鲜剂的创始人;参加并领导世界首次人工合成酵母丙氨酸转移核糖核酸(tRNA)的研究工作;人工合成了具有生物活性的酵母丙氨酸tRNA,使我国人工合成生物大分子的研究水平继续居于世界领先地位,在这项研究中从方案设计到具体路线的制订以及许多技术难关的解决,他都发挥了重要作用;1982年起从事酵母丙氨酸tRNA结构功能的关系和tRNA中修饰核苷酸的生物功能等方面的研究。

1980年当选为中国科学院院士(学部委员)。

Biochemist. Born in Taixing, Jiangsu Province. Graduated from Chongqing Central University in 1940. Received Ph. D. from Western Reserve University, USA in 1951. Undertook postdoctoral research in Johns Hopkins University from 1951 to 1954. Research professor, Shanghai Institute of Biochemistry, Chinese Academy of Sciences.

Wang determined the position of the third phosphopate in CoA and first established the method for large scale preparation of CoE Ⅱ(NADP+) directly from CoE Ⅰ(NADP+), which has been adopted by many large pharmaceutical factories over the world in the past 30 years. He was the pioneer in China in the initiator in the production of flavor-enhancing nucleotides. He participated and led the research on the total synthesis of yeast alanine transfer RNA(tRNA) for the first time in the world, which made China’s research on the biomacromolecular synthesis rank the world leading position. In this project, he played an important role in designing both the program and the detailed pathway as well as in tackling with many technological difficulties. Since 1982, he has been studying the relations between the structure and function of yeast alanine tRNA, biological function of the modified nucleotides in tRNA, etc..

He was elected Member of the Chinese Academy of Sciences in 1980.

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