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Construction of an M1 macrophage-related lncRNA signature for predicting the tumor immune microenvironment

2023-11-08QiWuYimingLiuQingsongHuandHuihuiWu

中国科学技术大学学报 2023年9期

Qi Wu, Yiming Liu, Qingsong Hu, and Huihui Wu

School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China

Graphical abstract

Bioinformatic analysis screened a 7-lncRNA signature that predicted M1 macrophage infiltration and prognosis.

Public summary

■ A total of 7 prognosis-related lncRNAs were screened and constructed as a prediction signature.

■ The 7-lncRNA signature precisely predicts the tumor-associated immune microenvironment.

■ The tumor mutation landscape was depicted based on the 7-lncRNA signature.