短波紫外线治疗小儿疱疹性口腔炎的疗效和安全性

刘丽艳 李继安 聂秀真 王少宁 林爱伟

[摘要] 目的 探讨短波紫外线治疗小儿疱疹性口腔炎的疗效和安全性。 方法 选取2019年1月至2020年5月期间入住我院的疱疹性口腔炎患兒112例为研究对象，随机分为对照组与试验组，每组各56例。对照组给予抗病毒、口腔护理和维持水电解质平衡等常规治疗，试验组在对照组治疗基础上加用短波紫外线口腔局部照射，每天1次，每次4～6 s，连用5 d。比较两组患儿的总有效率、热退时间、食欲改善时间、疱疹消失时间及溃疡发生率。观察短波紫外线口腔局部照射的副反应。 结果 试验组患儿的热退时间、食欲改善时间及口腔疱疹消退时间均明显短于对照组，差异有统计学意义（P<0.05）。试验组口腔溃疡发生率明显低于对照组，差异有统计学意义（P<0.05）。试验组治疗总有效率为92.9%，对照组为78.6%，试验组明显高于对照组，差异有统计学意义（P<0.05）。短波紫外线治疗口腔疱疹及溃疡无不适和疼痛，未发现明显副作用。 结论 药物配合短波紫外线局部照射治疗小儿疱疹性口腔炎安全、有效。

[关键词] 短波紫外线;治疗;小儿;疱疹性口腔炎;疗效;副作用

[中图分类号] R725.1          [文献标识码] B          [文章编号] 1673-9701（2021）24-0082-04

Efficacy and safety of shortwave ultraviolet in the treatment of herpetic stomatitis in children

LU Liyan   LI Ji′an   NIE Xiuzhen   WANG Shaoning   LIN Aiwei

Department of Infectious Diseases， Ji′nan Children′s Hospital， Ji′nan   250022， China

[Abstract] Objective To explore the efficacy and safety of shortwave ultraviolet in the treatment of herpetic stomatitis in children. Methods A total of 112 children with herpetic stomatitis who were admitted to our hospital from January 2019 to May 2020 were selected as the research subjects，and they were randomly divided into the control group and the experimental group，with 56 cases in each group. The control group was given conventional treatments such as antiviral，oral care，and maintaining water and electrolyte balance.The experimental group was given shortwave ultraviolet local oral irradiation on the basis of the control treatment， once a day， 4-6 seconds each time， five days in a row. The total effective rate， the antipyretic time， the time of appetite improvement， the time of herpes disappearance， and the incidence of ulcers were compared between the two groups. The side effects of local shortwave ultraviolet radiation in the oral cavity were observed. Results The antipyretic time， appetite improvement time， and oral herpes subsidence time of the children in the experimental group were significantly shorter than those of the control group， and the difference was statistically significant（P<0.05）. The incidence of oral ulcers in the experimental group was significantly lower than that in the control group， and the difference was also statistically significant （P<0.05）. The total effective rate of treatment in the experimental group was 92.9%， and the total effective rate in the control group was 78.6%. The total effective rate of the experimental group was significantly higher than that of the control group， and the difference was statistically significant（P<0.05）. There was no discomfort and pain in the treatment of oral herpes and ulcers with shortwave ultraviolet rays， and no obvious side effects were found. Conclusion Drugs combined with shortwave ultraviolet local irradiation are safe and effective in the treatment of herpetic stomatitis in children.