结核性胸膜炎病人给予醋酸泼尼松片联合抗痨药物治疗的临床分析

罗勇

【摘 要】

目的：探讨醋酸泼尼松片联合抗痨药物治疗结核性胸膜炎的临床效果。方法：选取近两年在我院接受治疗的70例结核性胸膜炎患者作为研究对象，按照随机数字表达法将其分为观察组与参考组，各为35例。观察组采用醋酸泼尼松片联合抗痨药物治疗，参考组仅采用常规抗痨药物治疗，比较两组治疗效果。结果：观察组治疗总有效率、胸腔积液吸收率均明显高于参考组（P<0.05）；观察组胸腔积液平均吸收时间明显短于参考组（P﹤0.05）；治疗后，观察组外周血干扰素（IFN-）、白细胞介素-2（IL-2）、白介素-6（IL-6）、C-反应蛋白（CRP）、降钙素原（PCT）水平均明显低于参考组（P﹤0.05）；两组治疗期间不良反应发生率比较无统计学意义（P﹥0.05）。结论：醋酸泼尼松片联合抗痨药物治疗结核性胸膜炎效果确切，能够促进胸腔积液吸收、提高患者免疫力，安全性高，可作为有效联合治疗方案推广。

【关键词】结核性胸膜炎；醋酸泼尼松片；抗痨药物

Clinical analysis of prednisone acetate combined with anti-tuberculosis drugs in tuberculous pleurisy patients

Luo yong

People's hospital of ganzi county， ganzi prefecture， sichuan 626700， China

Abstract Objective：

to investigate the clinical effect of prednisone acetate tablets combined with anti-tuberculosis drugs in the treatment of tuberculous pleurisy. Methods： 70 cases of tuberculous pleurisy patients who received treatment in our hospital in the past two years were selected as the research objects. According to the random number expression method， they were divided into observation group and reference group， with 35 cases each. The observation group was treated with prednisone acetate tablets combined with anti-tuberculosis drugs， while the reference group was only treated with conventional anti-tuberculosis drugs， and the therapeutic effects of the two groups were compared. Results： the total effective rate and the absorptivity of pleural effusion in the observation group were significantly higher than those in the reference group （P<0.05）. Less than 0.05， the average absorption time of pleural effusion of observation group is less than that of reference group （P < 0.05）. After treatment， the observation group of peripheral blood interferon （IFN - ）， interleukin 2 （IL 2） and interleukin 6 （IL 6） and C - reactive protein （CRP）， calcitonin （PCT） level were significantly lower than the reference group （P ﹤ 0.05）. The incidence of adverse reactions between the two groups during the treatment period showed no statistical significance （P > 0.05）. Conclusion： prednisone acetate combined with anti-tuberculosis drugs is effective in the treatment of tuberculous pleurisy， can promote the absorption of pleural effusion， improve the immunity of patients， high safety， can be used as an effective combined treatment scheme.

Key words： tuberculous pleurisy； Prednisone acetate tablets； The chemotherapy drugs

【中圖分类号】 R249

【文献标识码】 A

【文章编号】 1672-3783（2019）02-03-040-01