Iontophoretic Delivery of Riboflavin into the Rabbit Cornea:a Primary Study
2014-09-17NaLiXiujunPengZhengjunFanYuXia
Na Li, Xiujun Peng, Zhengjun Fan, Yu Xia
1 Chinese PLA Medical School& PLA General Hospital,Beijing 100853, China
2 Departmentof Ophthalmology,Navy General Hospital of Chinese PLA,Beijing 100048,China
Materials and methods
Study subjects
Iontophoresis
Instillation after de-epithelium
Slit-lamp exam ination
Corneal stroma button exam ination
Statistical analysis
Results
Discussion
Figure 1 The different yellow colored corneal stroma buttons in four groups.A:0.1%riboflavin-BSS by iontophoresis,B:0.1%riboflavin-saline solution by iontophoresis,C:0.1%riboflavin-distilled water solution by iontophoresis,D:conventional riboflavin instillation after de-epithelialization as controls.
Table 1 Yellow degree of rabbit corneal stroma after iontophoretic delivery by slit lamp exam ination
Table 2 Yellow degree of rabbit aqueous humor after iontophoretic delivery by slit lamp exam ination
Table 3 Yellow degree of rabbit corneal stroma button after iontophoretic delivery
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