聚维酮碘冲洗液在内眼手术前结膜囊病患者中的消毒效果及舒适度观察

孙溯荫　廖丽　韦兰

【摘要】 目的：觀察聚维酮碘冲洗液在内眼手术前结膜囊病患者中的消毒效果及舒适度。方法：选取2018年1月-2019年1月于本院进行内眼手术的患者58例（58眼）为研究对象，按照随机数字表法将其分为观察组和对照组，各29例（29眼）。两组术前1 d均给予0.5%左氧氟沙星滴眼液点眼8次，在此基础上，对照组术前1 h使用2.5 g/L安尔碘Ⅲ 10 mL+0.9%氯化钠注射液200 mL冲洗结膜囊，观察组术前1 h给予5%聚维酮碘10 mL+0.9%氯化钠注射液200 mL配置成0.025%的聚维酮碘溶液100 mL进行结膜冲洗。观察两组冲洗前后结膜囊带菌率、冲洗后结膜充血情况、不良反应发生率以及舒适度。结果：两组冲洗前带菌率比较，差异无统计学意义（P>0.05），观察组冲洗后带菌率为6.90%，低于对照组的27.59%，差异有统计学意义（P<0.05）;两组冲洗后结膜充血程度、不良反应发生率、舒适度评分比较，差异均无统计学意义（P>0.05）。结论：聚维酮碘冲洗液能够明显降低内眼手术患者术前结膜囊带菌率，且具有较好的安全性和舒适度，值得临床推广应用。

【关键词】 聚维酮碘冲洗液; 内眼手术; 结膜囊; 消毒; 舒适度

【Abstract】 Objective：To observe the disinfection effect and comfort of Povidone Iodine Rinse Solution in patients with conjunctival sac disease before internal eye surgery.Method：A total of 58 patients（58 eyes）who underwent endophthalmic surgery in our hospital from January 2018 to January 2019 were selected as the subjects.According to random number table method，they were divided into observation group and control group，29 cases（29 eyes）in each group.They were given 0.5% Levofloxacin eye drops 8 times 1 day before operation，on this basis，control group was given 2.5 g/L AneriodineⅢ 10 mL + 0.9% Sodium Chloride Injection 200 mL to wash conjunctival sac 1 hour before operation，observation group was given 5% Povidone Iodine Rinse Solution 10 mL + 0.9% Sodium Chloride Injection 200 mL，which was allocated to 0.025% povidone iodine solution 100 mL for conjunctival irrigation.The bacterial carrier rate of conjunctival sac before and after irrigation，conjunctival congestion after irrigation，incidence of adverse reactions and comfort were observed.Result：Before irrigation，the rate of bacteria carrying in two groups was compared，the difference was not statistically significant（P>0.05）;after irrigation，the rate of bacteria carrying in observation group was 6.90%，lower than 27.59% in control group，the difference was statistically significant（P<0.05）.The degree of conjunctival congestion，incidence of adverse reactions and comfort scores in two groups were compared，the differences were not statistically significant（P>0.05）.Conclusion：Povidone Iodine Rinse Solution can significantly reduce the bacterial carrier rate of conjunctival sac before internal eye surgery，and has good safety and comfort，which is worthy of clinical application.

【Key words】 Povidone Iodine Rinse Solution; Internal eye surgery; Conjunctival sac; Disinfection;Comfort

First-authors address：Peoples Hospital of Xinyi City，Xinyi 525300，China