地塞米松注射液在呼吸道感染患者中的应用效果
2019-04-10荣峰
荣峰
[摘要]目的 探讨地塞米松注射液在呼吸道感染患者中的应用效果。方法 选取我院2016年5月~2018年5月收治的120例呼吸道感染患者作为研究对象,按照不同治疗方法分为治疗组(60例)与对照组(60例)。治疗组采用对症治疗联合地塞米松注射液治疗,对照组仅采用单纯对照治疗。比较两组的体温恢复情况、不良反应发生情况、生活质量SF-36评分。结果 治疗组的体温恢复时间、治疗时间均短于对照组,差异有统计学意义(P<0.05);治疗组的不良反应总发生率高于对照组,差异有统计学意义(P<0.05);治疗组治疗后的生活质量SF-36评分高于对照组,差异有统计学意义(P<0.05)。结论 临床对呼吸道感染患者采用地塞米松注射液治疗,虽可加速体温恢复正常,从而提高生活质量,但值得注意的是,其不良反应发生率较高,建议谨慎使用。
[關键词]呼吸道感染;地塞米松注射液;不良反应;对症治疗
[中图分类号] R56 [文献标识码] A [文章编号] 1674-4721(2019)2(a)-0048-03
[Abstract] Objective To explore the application effect of Dexamethasone Injection in patients with respiratory tract infection. Methods A total of 120 patients with respiratory tract infection admitted to our hospital from May 2016 to May 2018 were selected as study subjects, and divided into the treatment group (60 cases) and the control group (60 cases) according to different treatment methods. Symptomatic treatment combined with Dexamethasone Injection was used in the treatment group, while the control group was only treated with simple control. Temperature recovery, adverse reactions, and quality of life SF-36 scores were compared between the two groups. Results The temperature recovery time and treatment time of the treatment group were shorter than those of the control group, and the differences were statistically significant (P<0.05). The total incidence rate of adverse reaction of the treatment group was higher than that of the control group, and the difference was statistically significant (P<0.05). Quality of life SF-36 score in the treatment group after treatment was higher than that in the control group, the difference was statistically significant (P<0.05). Conclusion Dexamethasone Injection can accelerate the recovery of body temperature and improve the quality of life in patients with respiratory tract infection. However, it is worth noting that the adverse reaction rate is relatively high and it is recommended to be used cautiously.
[Key words] Respiratory tract infection; Dexamethasone Injection; Adverse reactions; Symptomatic treatment
上呼吸道感染是指咽喉部、鼻腔引发急性炎症所致,具有较高的患病率,特别是在流行性感染高发时段或者是春、冬两季[1]。该病的传染性较强,若未能得到及时且有效控制,则容易产生诸多严重并发症,对患者正常生活、工作水平产生影响,因此,加强早期预防与控制呼吸道感染病症对加速患者早日恢复身体健康具有重大积极意义。目前,本病临床中常用常规抗感染治疗,虽具有一定成效,但效果不明显。地塞米松属于一种糖皮质激素类药物,可发挥抗休克、抗炎、抗过敏等药物作用[2-3]。但多项临床实践显示,该药的不良反应较多,受到医学界高度重视。本研究选取我院收治的呼吸道感染患者作为研究对象,旨在探讨地塞米松注射液治疗的临床现实意义,并评价治疗后的不良反应发生情况,现报道如下。
1资料与方法
1.1一般资料
随机选取2016年5月~2018年5月我院收治的120例呼吸道感染患者作为研究对象,依照不同治疗方案分为治疗组和对照组,各60例。治疗组中,男34例,女26例;年龄20~75岁,平均(43.11±6.38)岁。对照组中,男35例,女25例;年龄18~73岁,平均(43.05±6.13)岁。所有患者均伴有程度不一的咳嗽、咳痰、发热、鼻塞等临床病症。两组的一般资料比较,差异无统计学意义(P>0.05),具有可比性。纳入标准:①确诊为呼吸道感染者;②积极配合本次临床试验者;③无其他严重并发症者;④所有患者均已签署知情同意书,且经医院医学伦理委员会审核批准。排除标准:①患有严重心血管疾病者;②年龄<15周岁者;③患有严重精神类疾病者。