胺碘酮治疗冠心病急性心肌梗死伴高危快速型心律失常的临床研究

张爱菊

【摘要】 目的 探討冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治疗的临床效果。方法 70例冠心病急性心肌梗死伴高危快速型心律失常患者作为研究对象， 随机分为对照组和观察组， 每组35例， 对照组采用普鲁卡因胺治疗， 观察组采用胺碘酮进行治疗， 比较两组治疗效果。结果 观察组治疗总有效率为94.29%， 明显高于对照组的74.29%， 差异具有统计学意义（χ2=5.285， P=0.022<0.05）。观察组不良反应发生率为8.57%， 明显低于对照组的28.57%， 差异具有统计学意义（χ2=4.629， P=0.031<0.05）。结论 冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治疗效果显著， 具有较高安全性， 可推广应用。

【关键词】 胺碘酮；冠心病；心肌梗死；高危快速型心律失常；效果

DOI：10.14163/j.cnki.11-5547/r.2017.23.059

Clinical research of amiodarone in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia ZHANG Ai-ju. Jilin Songyuan City Central Hospital， Songyuan 138000， China

【Abstract】 Objective To investigate clinical effect by amiodarone in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia. Methods A total of 70 coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia patients as study subjects were randomly divided into control group and observation group， with 35 cases in each group. The control group received procainamide for treatment， and the observation group received amiodarone for treatment. Comparison was made on curative effects between the two groups. Results The observation group had obviously higher total effective rate in treatment as 94.29% than 74.29% in the control group， and their difference had statistical significance （χ2=5.285， P=0.022<0.05）. The observation group had much lower incidence of adverse reactions as 8.57% than 28.57% in the control group， and their difference had statistical significance （χ2=4.629， P=0.031<0.05）. Conclusion Implement of amiodarone shows excellent curative effect in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia， along with high safety. This method is worth promoting and applying.

【Key words】 Amiodarone； Coronary heart disease； Myocardial infarction； High-risk tachyarrhythmia； Effectendprint