Evaluation of Tear Malate Dehydrogenase 2 in Mild Dry Eye Disease

Qing Guo， Houbin Huang， Yuli Pi， Hancheng Zhang

1 Department of Ophthalmology， First Hospital Affiliated to Chinese PLA General Hospital， Beijing 100048，China

2 Department of Ophthalmology，Chinese PLA General Hospital，Beijing 100853，China

3 Department of Ophthalmology，Zhujiang Hospital，Southern Medical University，Guangzhou 510280，China

Introduction

Material and methods

Subjects

Tear collection

Diagnostic tests of DE and determination of tear MDH and MDH2 activities

Statistical analysis

Results

Characteristics of the study population

Table 1 Characteristics of the study group

Activities of tear MDH and MDH2

Figure 1 Relative activities of tear MDH isoforms

Correlation analysis of tear MDH2 activities with symptoms and diagnostic tests

Table 2 Changes in tear MDH activities， MDH2 activities， and clinical test parameters

Discussion

Table 3 Correlation analysis of tear MDH2 activities and symptoms