Preface

1. Preface for special issue on new analytical techniques and methods in drug metabolism and pharmacokinetics

Review Papers

1. Current status and future directions of high-throughput ADME screening in drug discovery
2. Current LC-MS-based strategies for characterization and quantification of antibody-drug conjugates
3. Current status of in vivo bioanalysis of nano drug delivery systems

Original Articles

1. Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS
2. Software-aided detection and structural characterization of cyclic peptide metabolites in biological matrix by high-resolution mass spectrometry
3. Quantitation of DNA by nuclease P1 digestion and UPLC-MS/MS to assess binding efficiency of pyrrolobenzodiazepine
4. Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines
5. An ultra-sensitive and easy-to-use assay for sensing human UGT1A1 activities in biological systems

Short Communication

1. Screening of the whole human cytochrome P450 complement(CYPome)with enzyme bag cocktails