EDITORIAL

1. Next-generation antibody–drug conjugates revolutionize the precise classification and treatment of HER2-expressing breast cancer
2. Immunotherapy for multiple myeloma: new chances and hope
3. Recent advances in the systemic treatment of gastrointestinal stromal tumors
4. Opportunities and challenges of immunotherapy for dMMR/MSI-H colorectal cancer
5. Cohort profile: design and methods of the Chinese colorectal,breast, lung, liver, and stomach cancer screening trial(C-BLAST)

PERSPECTIVE

1. Recent research hotspots in sequencing and the pancreatic neuroendocrine tumor microenvironment

REVIEW

1. Emerging roles of plasmacytoid dendritic cell crosstalk in tumor immunity
2. Targeting endoplasmic reticulum stress signaling in ovarian cancer therapy

ORIGINAL ARTICLE

1. Efficacy and safety of gemcitabine plus S-1 vs.gemcitabine plus nab-paclitaxel in treatment-naïve advanced pancreatic ductal adenocarcinoma