REVIEWS

1. Current understanding of osteoarthritis pathogenesis and relevant new approaches
2. Biomechanics and mechanobiology of the bone matrix
3. Can intracellular Staphylococcus aureus in osteomyelitis be treated using current antibiotics?A systematic review and narrative synthesis
4. Insights into skeletal stem cells
5. Changes in interstitial fluid flow,mass transport and the bone cell response in microgravity and normogravity

ORIGINAL ARTICLES

1. Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx− /−mice
2. FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritis
3. Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation
4. Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5
5. Simultaneous augmentation of muscle and bone by locomomimetism through calcium-PGC-1α signaling
6. GsαR201C and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells
7. Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration
8. Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation
9. Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway
10. Endothelial PDGF-BB/PDGFR-β signaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation
11. Fetuin-A is an immunomodulator and a potential therapeutic option in BMP4-dependent heterotopic ossification and associated bone mass loss
12. Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP,TGFβ,and Wnt signaling in articular cartilage formation and osteoarthritis